Coxoauricular syndrome is a rare genetic disorder characterized by a combination of craniofacial, skeletal, and cardiovascular abnormalities. It is caused by a mutation in the gene encoding the protein filamin A. Symptoms may include cleft lip and/or palate, hearing loss, heart defects, and skeletal abnormalities. Treatment is based on the individual's symptoms and may include surgery, hearing aids, and medications.

The symptoms of Coxoauricular Syndrome vary depending on the severity of the condition, but may include:

- Abnormal facial features, such as a wide-set eyes, a flat nasal bridge, and a small chin
- Low-set ears
- Hearing loss
- Heart defects, such as atrial septal defect, ventricular septal defect, and patent ductus arteriosus
- Abnormalities of the kidneys and urinary tract
- Abnormalities of the gastrointestinal tract
- Abnormalities of the skeletal system, such as Scoliosis and joint contractures
- Intellectual disability
- Seizures
- Abnormalities of the skin, such as Thickened skin on the palms and soles of the feet
- Abnormalities of the eyes, such as strabismus and cataracts

Coxoauricular syndrome is a rare genetic disorder caused by a mutation in the GATA4 gene. This gene is responsible for the development of the heart and other organs. The mutation can cause a variety of symptoms, including heart defects, hearing loss, and facial abnormalities. Other causes of Coxoauricular syndrome include chromosomal abnormalities, such as trisomy 21 (Down syndrome), and environmental factors, such as exposure to certain medications or toxins.

The treatment for Coxoauricular syndrome depends on the severity of the symptoms and the underlying cause. Treatment may include:

1. Surgery to repair the affected structures.

2. Physical therapy to improve range of motion and strength.

3. Medications to reduce inflammation and pain.

4. Occupational therapy to help with activities of daily living.

5. Speech therapy to improve communication.

6. Assistive devices such as splints or braces to support the affected area.

7. Counseling to help with emotional and psychological issues.

1. Genetic predisposition
2. Exposure to certain medications or toxins
3. Congenital heart defects
4. Premature birth
5. Low birth weight
6. Maternal infections during pregnancy
7. Exposure to certain viruses
8. Exposure to loud noises
9. Exposure to secondhand smoke
10. Poor nutrition during pregnancy

At this time, there is no known cure for Coxoauricular Syndrome. However, there are medications that can be used to help manage the symptoms of the condition. These medications include anticonvulsants, muscle relaxants, and anti-inflammatory drugs. Additionally, physical therapy and occupational therapy can be used to help improve mobility and reduce pain.