Congenitally uncorrected transposition of the great arteries with cardiac malformation is a rare congenital heart defect in which the two main arteries of the heart, the aorta and the pulmonary artery, are switched in position. This means that the aorta, which normally carries oxygen-rich blood from the heart to the body, is connected to the right ventricle, and the pulmonary artery, which normally carries oxygen-poor blood from the heart to the lungs, is connected to the left ventricle. This defect can cause a variety of cardiac malformations, including ventricular septal defect, atrial septal defect, and patent ductus arteriosus.

Symptoms of Congenitally uncorrected transposition of the great arteries with cardiac malformation can include:

- Rapid breathing
- Poor feeding
- Sweating
- Cyanosis (bluish discoloration of the skin)
- Poor weight gain
- Heart murmur
- Low blood pressure
- Fatigue
- Poor circulation
- Abnormal heart rhythms
- Heart failure

The exact cause of congenitally uncorrected transposition of the great arteries with cardiac malformation is unknown. However, some potential causes may include genetic mutations, environmental factors, and maternal health conditions such as diabetes, obesity, and drug use.

1. Surgery: The most common treatment for congenitally uncorrected transposition of the great arteries with cardiac malformation is a surgical procedure called an arterial switch operation. This procedure involves switching the positions of the two main arteries in the heart, the aorta and the pulmonary artery.

2. Catheterization: In some cases, a catheterization procedure may be used to treat congenitally uncorrected transposition of the great arteries with cardiac malformation. This procedure involves inserting a thin tube into the heart to open up blocked or narrowed arteries.

3. Medication: Medications may be prescribed to help manage symptoms associated with congenitally uncorrected transposition of the great arteries with cardiac malformation. These medications may include diuretics, beta-blockers, and ACE inhibitors.

4. Pac

1. Maternal diabetes
2. Maternal use of certain medications during pregnancy
3. Maternal alcohol or drug use during pregnancy
4. Maternal age over 35
5. Maternal obesity
6. Maternal smoking during pregnancy
7. Family history of congenital heart defects
8. Exposure to certain environmental toxins
9. Chromosomal abnormalities
10. Genetic syndromes

Yes, there are treatments available for Congenitally uncorrected transposition of the great arteries with cardiac malformation. The most common treatment is a procedure called an arterial switch operation (ASO). This procedure involves switching the positions of the two main arteries in the heart, the aorta and the pulmonary artery. This allows the oxygen-rich blood to flow to the body and the oxygen-poor blood to flow to the lungs. Other treatments may include medications to help manage symptoms, such as heart failure, and other procedures to correct any other cardiac malformations.