Congenital pseudoarthrosis of the clavicle is a rare condition in which the clavicle (collarbone) fails to form properly during fetal development. This results in a weak or absent connection between the two ends of the clavicle, causing the bone to be unstable and prone to fracture. Symptoms may include pain, swelling, and deformity of the affected area. Treatment typically involves surgical repair of the clavicle.

The most common symptom of congenital pseudoarthrosis of the clavicle is a visible deformity of the clavicle, which may appear as a bump or lump on the shoulder. Other symptoms may include pain, tenderness, and limited range of motion in the shoulder. In some cases, the deformity may be accompanied by a clicking or grinding sound when the shoulder is moved.

The exact cause of congenital pseudoarthrosis of the clavicle is unknown. However, it is believed to be related to a genetic defect or a developmental abnormality. Other possible causes include trauma, infection, or a metabolic disorder.

1. Non-surgical treatment:

- Physical therapy to improve range of motion and strength
- Bracing to support the affected area
- Pain medications to reduce discomfort

2. Surgical treatment:

- Open reduction and internal fixation (ORIF) to stabilize the clavicle
- Bone grafting to fill in the gap between the two ends of the clavicle
- Arthrodesis to fuse the two ends of the clavicle together
- Osteotomy to realign the clavicle

1. Premature birth
2. Low birth weight
3. Genetic predisposition
4. Maternal smoking during pregnancy
5. Maternal alcohol consumption during pregnancy
6. Maternal diabetes during pregnancy
7. Maternal thyroid disease during pregnancy
8. Maternal use of certain medications during pregnancy
9. Maternal infection during pregnancy
10. Family history of congenital pseudoarthrosis of the clavicle

At this time, there is no known cure for congenital pseudoarthrosis of the clavicle. Treatment typically involves surgical intervention to stabilize the clavicle and prevent further damage. Medications such as non-steroidal anti-inflammatory drugs (NSAIDs) may be prescribed to reduce pain and inflammation. Physical therapy may also be recommended to help strengthen the muscles around the affected area.