Classic progressive supranuclear palsy (PSP) is a rare neurological disorder that affects movement, balance, and other basic functions. It is a type of atypical parkinsonism, meaning it is similar to Parkinson's disease but has different symptoms. Symptoms of PSP include difficulty with balance and walking, changes in vision, difficulty speaking and swallowing, and changes in behavior. PSP is a progressive disorder, meaning it gets worse over time. There is no cure for PSP, but medications and therapies can help manage symptoms.

The main symptoms of classic progressive supranuclear palsy syndrome include:

- Loss of balance and coordination
- Difficulty walking
- Slurred speech
- Difficulty swallowing
- Blurred vision
- Loss of facial expression
- Difficulty with eye movements
- Cognitive decline
- Depression
- Urinary incontinence
- Muscle Stiffness and spasms
- Loss of appetite
- Fatigue

Classic progressive supranuclear palsy syndrome is caused by a buildup of abnormal proteins in the brain, specifically tau proteins. This buildup of proteins leads to the death of nerve cells in the brain, which causes the symptoms of the condition. The exact cause of the buildup of tau proteins is unknown, but it is believed to be related to genetic and environmental factors.

1. Medications: Medications can be used to help manage the symptoms of classic progressive supranuclear palsy syndrome. These include medications to help with movement, such as levodopa, anticholinergics, and dopamine agonists. Other medications may be used to help with depression, anxiety, and sleep disturbances.

2. Physical Therapy: Physical therapy can help improve balance, coordination, and strength. It can also help with activities of daily living, such as walking, dressing, and eating.

3. Speech Therapy: Speech therapy can help with communication difficulties, such as slurred speech and difficulty swallowing.

4. Occupational Therapy: Occupational therapy can help with activities of daily living, such as dressing, bathing, and eating.

5. Assistive Devices: Assistive devices, such as walkers,

1. Age: Classic progressive supranuclear palsy syndrome is most commonly seen in people over the age of 60.

2. Gender: Men are more likely to develop classic progressive supranuclear palsy syndrome than women.

3. Genetics: Certain genetic mutations have been linked to an increased risk of developing classic progressive supranuclear palsy syndrome.

4. Exposure to certain toxins: Exposure to certain toxins, such as pesticides, may increase the risk of developing classic progressive supranuclear palsy syndrome.