Classic Hodgkin lymphoma, mixed cellularity type is a type of Hodgkin lymphoma, a cancer of the lymphatic system. It is characterized by the presence of two types of cells, Reed-Sternberg cells and a mixture of other cells, including lymphocytes, eosinophils, and histiocytes. It is the most common type of Hodgkin lymphoma, accounting for about 40% of all cases. Symptoms of classic Hodgkin lymphoma, mixed cellularity type may include swollen lymph nodes, fever, night sweats, and weight loss. Treatment typically involves chemotherapy and/or radiation therapy.