Charcot-Marie-Tooth Disease (CMT) is a group of inherited neurological disorders that affect the peripheral nerves. It is the most common inherited neurological disorder, affecting an estimated 1 in 2,500 people worldwide. Symptoms of CMT include muscle weakness and wasting, foot deformities, and impaired sensation in the feet, legs, and hands. CMT is caused by mutations in genes that are responsible for the production of proteins that are important for the structure and function of peripheral nerves. Treatment for CMT is focused on managing symptoms and preventing further nerve damage.