The treatments for Chanarin-Dorfman Syndrome vary depending on the individual and the severity of the condition. Generally, treatments may include dietary changes, physical therapy, medications, and/or surgery. Dietary changes may include reducing the amount of fat in the diet, increasing the amount of carbohydrates, and avoiding certain foods that may trigger symptoms. Physical therapy may help to improve muscle strength and coordination. Medications may be prescribed to help reduce inflammation and improve muscle strength. Surgery may be necessary to correct any structural abnormalities.