Treatment for CEBPE-associated autoinflammation-immunodeficiency-neutrophil dysfunction syndrome typically involves a combination of medications and lifestyle changes. Medications may include corticosteroids, immunosuppressants, and biologic agents. Lifestyle changes may include avoiding triggers such as infections, stress, and certain foods. Other treatments may include physical therapy, occupational therapy, and speech therapy. In some cases, surgery may be necessary to correct any underlying structural issues.