Camptodactyly Syndrome, Guadalajara Type 2 (CSG2) is a rare genetic disorder characterized by the permanent flexion of the fingers and toes, as well as other skeletal abnormalities. It is caused by a mutation in the gene encoding the protein filamin A (FLNA). Symptoms of CSG2 include camptodactyly (permanent flexion of the fingers and toes), joint contractures, scoliosis, and facial dysmorphism. Other features may include short stature, intellectual disability, and cardiac and renal abnormalities. Treatment is supportive and may include physical therapy, splinting, and orthopedic surgery.

The symptoms of Camptodactyly Syndrome, Guadalajara Type 2 (CSG2) include:

-Flexion contractures of the fingers and toes
-Abnormal curvature of the fingers and toes
-Abnormal joint mobility
-Abnormal joint stability
-Abnormal joint laxity
-Abnormal joint stiffness
-Abnormal joint swelling
-Abnormal joint pain
-Abnormal joint deformity
-Abnormal joint crepitus
-Abnormal joint instability
-Abnormal joint range of motion
-Abnormal joint tenderness
-Abnormal joint instability
-Abnormal joint laxity
-Abnormal joint swelling
-Abnormal joint deformity
-Abnormal joint crepitus
-Abnormal joint instability
-Abnormal joint range of motion
-Abnormal joint

Camptodactyly syndrome, Guadalajara type 2 (CG2) is a rare genetic disorder caused by a mutation in the gene encoding the protein filamin A (FLNA). This mutation results in a decrease in the amount of filamin A protein in the body, which can lead to a variety of physical and neurological symptoms. The exact cause of the mutation is unknown, but it is believed to be inherited in an autosomal dominant pattern.

The treatments for Camptodactyly Syndrome, Guadalajara Type 2 (CGD2) vary depending on the severity of the condition. Generally, treatment focuses on managing the symptoms and improving the range of motion of the affected joints. This may include physical therapy, occupational therapy, splinting, and bracing. Surgery may be recommended in more severe cases to correct the deformity and improve joint function. In some cases, medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) may be prescribed to reduce pain and inflammation.

1. Genetic predisposition: Camptodactyly syndrome, Guadalajara type 2 is an autosomal recessive disorder, meaning that it is inherited from both parents.

2. Environmental factors: Exposure to certain environmental toxins or radiation may increase the risk of developing Camptodactyly syndrome, Guadalajara type 2.

3. Age: Camptodactyly syndrome, Guadalajara type 2 is more common in children and adolescents.

4. Gender: Camptodactyly syndrome, Guadalajara type 2 is more common in males than females.

At this time, there is no known cure for Camptodactyly Syndrome, Guadalajara type 2. However, there are medications and treatments that can help manage the symptoms. These include physical therapy, splinting, and medications such as botulinum toxin injections, nonsteroidal anti-inflammatory drugs, and muscle relaxants. Surgery may also be an option for some people.