Campomelia, Cumming type is a rare genetic disorder characterized by a combination of skeletal abnormalities, including short stature, short ribs, and a narrow chest. It is caused by a mutation in the gene encoding the protein filamin A. Symptoms may include short stature, skeletal abnormalities, and intellectual disability.

The symptoms of Campomelia, Cumming type include:

-Shortened limbs
-Underdeveloped or absent thumbs
-Underdeveloped or absent radius
-Underdeveloped or absent ulna
-Underdeveloped or absent humerus
-Underdeveloped or absent femur
-Underdeveloped or absent tibia
-Underdeveloped or absent fibula
-Underdeveloped or absent feet
-Underdeveloped or absent toes
-Underdeveloped or absent hands
-Underdeveloped or absent fingers
-Underdeveloped or absent wrists
-Underdeveloped or absent elbows
-Underdeveloped or absent shoulders
-Underdeveloped or absent hips
-Underdeveloped or absent knees
-Underdeveloped or absent ankles
-Underdeveloped or absent vertebrae
-Underdeveloped or absent ribs
-Underdeveloped or absent sternum
-Underdeveloped or absent pel

Campomelia, Cumming type is a rare congenital disorder caused by a mutation in the gene that codes for the protein filamin A. This mutation affects the development of the bones in the arms and legs, resulting in shortening of the limbs and other skeletal abnormalities. Other causes of Campomelia, Cumming type include chromosomal abnormalities, environmental factors, and genetic syndromes.

The treatments for Campomelia, Cumming type vary depending on the severity of the condition. Generally, treatment focuses on managing the symptoms and improving the quality of life of the affected individual. Treatment may include physical therapy, occupational therapy, orthopedic surgery, and bracing. In some cases, medications may be prescribed to help manage pain and improve mobility. Additionally, genetic counseling may be recommended for individuals and families affected by Campomelia, Cumming type.

1. Maternal diabetes
2. Maternal obesity
3. Maternal smoking
4. Maternal alcohol consumption
5. Maternal age over 35
6. Maternal exposure to certain medications
7. Maternal exposure to certain environmental toxins
8. Family history of Campomelia, Cumming type
9. Genetic mutations in certain genes, such as the GJA1 gene

Unfortunately, there is no cure for Campomelia, Cumming type. However, there are medications that can help manage the symptoms associated with the condition. These medications include muscle relaxants, anticonvulsants, and pain medications. Physical and occupational therapy can also help improve mobility and function.