About Brachydactyly type A7

What is Brachydactyly type A7?

Brachydactyly type A7 is a rare genetic disorder characterized by shortening of the middle phalanges of the fingers and toes. It is caused by a mutation in the HOXD13 gene. Symptoms may include shortening of the middle phalanges, a wide gap between the middle and distal phalanges, and a wide gap between the proximal and middle phalanges.

What are the symptoms of Brachydactyly type A7?

The most common symptoms of Brachydactyly type A7 are shortening of the middle phalanges of the fingers and toes, and a wide gap between the first and second phalanges. Other symptoms may include a wide gap between the second and third phalanges, a wide gap between the fourth and fifth phalanges, and a wide gap between the fifth and sixth phalanges. In some cases, the nails may be abnormally shaped or curved.

What are the causes of Brachydactyly type A7?

The exact cause of Brachydactyly type A7 is unknown. However, it is believed to be caused by a genetic mutation that affects the development of the bones in the hands and feet. It is also thought to be inherited in an autosomal dominant pattern, meaning that only one copy of the mutated gene is needed for a person to be affected by the condition.

What are the treatments for Brachydactyly type A7?

The treatment for Brachydactyly type A7 depends on the severity of the condition. In mild cases, no treatment may be necessary. In more severe cases, surgical options may be considered. These include bone lengthening procedures, tendon transfers, and joint fusion. In some cases, orthotic devices may be used to help improve the function of the affected hand or foot. Physical therapy may also be recommended to help improve range of motion and strength.

What are the risk factors for Brachydactyly type A7?

1. Family history of Brachydactyly type A7
2. Maternal diabetes
3. Maternal smoking
4. Maternal alcohol consumption
5. Maternal exposure to certain medications
6. Maternal exposure to certain environmental toxins
7. Maternal malnutrition
8. Maternal obesity
9. Maternal age
10. Genetic mutations

Is there a cure/medications for Brachydactyly type A7?

At this time, there is no known cure or medications for Brachydactyly type A7. Treatment for this condition is typically focused on managing the symptoms and improving the appearance of the affected digits. This may include physical therapy, splinting, and/or surgery.