Bolivian hemorrhagic fever (BHF) is a rare and potentially fatal viral disease caused by the Machupo virus, which is a member of the Arenaviridae family. It is found in Bolivia and parts of Paraguay and is spread by contact with infected rodents, their urine, or their droppings. Symptoms of BHF include fever, headache, muscle pain, nausea, vomiting, and bleeding from the nose, mouth, and other body parts. In severe cases, the virus can cause shock, organ failure, and death. Treatment is supportive and includes fluids, electrolytes, and blood transfusions. There is no specific antiviral treatment for BHF.