Blepharophimosis-ptosis-epicanthus inversus syndrome type 2 (BPES type 2) is a rare genetic disorder characterized by abnormal development of the eyelids, including blepharophimosis (narrowing of the eyelids), ptosis (drooping of the upper eyelids), and epicanthus inversus (inward folding of the inner corner of the eyelids). It is caused by mutations in the FOXL2 gene. Symptoms may include drooping of the upper eyelids, narrowing of the eyelids, and inward folding of the inner corner of the eyelids. Other features may include hearing loss, cleft palate, and abnormalities of the hands and feet. Treatment may include surgery to correct the eyelid abnormalities, hearing aids, and speech therapy.

The symptoms of Blepharophimosis-ptosis-epicanthus inversus syndrome type 2 (BPES2) include:

-Blepharophimosis (narrowing of the eyelids)
-Ptosis (drooping of the upper eyelids)
-Epicanthus inversus (inward turning of the inner corner of the eye)
-Downslanting palpebral fissures (the gap between the upper and lower eyelids)
-Strabismus (crossed eyes)
-Upper eyelid coloboma (a gap in the upper eyelid)
-Upper eyelid retraction (the upper eyelid is pulled up too high)
-Lower eyelid retraction (the lower eyelid is pulled down too low)
-Hypertel

Blepharophimosis-ptosis-epicanthus inversus syndrome type 2 is caused by mutations in the FOXL2 gene. This gene is responsible for the development of the eyelids and other structures of the face. Mutations in this gene can lead to the characteristic features of this syndrome, including blepharophimosis (narrowing of the eyelids), ptosis (drooping of the upper eyelids), and epicanthus inversus (inward folding of the skin at the inner corner of the eye).

1. Eyelid Surgery: This is the most common treatment for Blepharophimosis-ptosis-epicanthus inversus syndrome type 2. Surgery can help to correct the drooping eyelids and improve vision.

2. Botox Injections: Botox injections can be used to help relax the muscles around the eyes, which can help to improve the appearance of the eyes and reduce the drooping of the eyelids.

3. Eyeglasses: Eyeglasses can be used to help improve vision in cases of Blepharophimosis-ptosis-epicanthus inversus syndrome type 2.

4. Eye Drops: Eye drops can be used to help reduce the inflammation and irritation of the eyes.

5. Artificial Tears: Artificial tears can be used to help lubricate the

1. Genetic mutation in the FOXL2 gene
2. Family history of Blepharophimosis-ptosis-epicanthus inversus syndrome type 2
3. Female gender
4. Premature birth
5. Low birth weight
6. Exposure to certain medications during pregnancy
7. Exposure to certain environmental toxins during pregnancy

At this time, there is no known cure for Blepharophimosis-ptosis-epicanthus inversus syndrome type 2. However, there are medications and treatments available to help manage the symptoms. These include eye drops, ointments, and surgery to correct the eyelid deformities. Additionally, physical therapy and occupational therapy may be recommended to help improve vision and eye movement.