Blepharophimosis-ptosis-epicanthus inversus syndrome type 2 (BPES type 2) is a rare genetic disorder characterized by abnormal development of the eyelids, including blepharophimosis (narrowing of the eyelids), ptosis (drooping of the upper eyelids), and epicanthus inversus (inward folding of the inner corner of the eyelids). It is caused by mutations in the FOXL2 gene. Symptoms may include drooping of the upper eyelids, narrowing of the eyelids, and inward folding of the inner corner of the eyelids. Other features may include hearing loss, cleft palate, and abnormalities of the hands and feet. Treatment may include surgery to correct the eyelid abnormalities, hearing aids, and speech therapy.