Autosomal recessive secondary polycythemia not associated with VHL gene is a rare genetic disorder characterized by an increase in the number of red blood cells in the body. It is caused by mutations in genes other than the VHL gene, which is responsible for the more common form of secondary polycythemia. Symptoms of this disorder may include headaches, dizziness, fatigue, and shortness of breath. Treatment typically involves phlebotomy (removal of excess red blood cells) and medications to reduce the production of red blood cells.

The symptoms of Autosomal recessive secondary polycythemia not associated with VHL gene include:

-Headaches
-Dizziness
-Fatigue
-Shortness of breath
-Visual disturbances
-Nosebleeds
-Itching
-Enlarged spleen
-High blood pressure
-Abnormal blood clotting
-Abnormal red blood cell production
-Abnormal white blood cell production
-Abnormal platelet production
-Abnormal hemoglobin levels

1. Mutations in the EPOR gene, which is responsible for the production of erythropoietin, a hormone that stimulates red blood cell production.

2. Mutations in the JAK2 gene, which is involved in the regulation of red blood cell production.

3. Mutations in the VHL gene, which is responsible for the regulation of oxygen levels in the body.

4. Abnormalities in the spleen, which can lead to increased red blood cell production.

5. Abnormalities in the kidneys, which can lead to increased red blood cell production.

6. Abnormalities in the liver, which can lead to increased red blood cell production.

7. Abnormalities in the bone marrow, which can lead to increased red blood cell production.

8. Exposure

1. Phlebotomy: This is a procedure in which a small amount of blood is removed from the body to reduce the number of red blood cells.

2. Hydroxyurea: This is a medication that is used to reduce the production of red blood cells.

3. Interferon-alpha: This is a medication that is used to reduce the production of red blood cells.

4. Anagrelide: This is a medication that is used to reduce the production of red blood cells.

5. Ruxolitinib: This is a medication that is used to reduce the production of red blood cells.

6. Aspirin: This is a medication that is used to reduce the risk of blood clots.

7. Diet and lifestyle changes: Making changes to your diet and lifestyle

1. Inherited genetic mutations in the EPOR gene
2. Inherited genetic mutations in the JAK2 gene
3. Inherited genetic mutations in the MPL gene
4. Inherited genetic mutations in the TET2 gene
5. Inherited genetic mutations in the CALR gene
6. Inherited genetic mutations in the CBL gene
7. Inherited genetic mutations in the PTPN11 gene
8. Inherited genetic mutations in the NF1 gene
9. Inherited genetic mutations in the EGLN1 gene
10. Inherited genetic mutations in the HIF2A gene
11. Inherited genetic mutations in the VHL gene
12. Exposure to certain environmental toxins
13. Exposure to certain medications
14. Exposure to certain radiation sources
15. Advanced age
16. Family history of the

At this time, there is no known cure for autosomal recessive secondary polycythemia not associated with VHL gene. Treatment typically involves managing the underlying cause of the condition, such as reducing the amount of oxygen in the blood, or treating any underlying medical conditions that may be contributing to the condition. Medications such as diuretics, anticoagulants, and anti-inflammatory drugs may also be used to help manage symptoms.