Autosomal recessive generalized dystrophic epidermolysis bullosa, intermediate form (AR-GDEB-IF) is a rare genetic disorder that affects the skin and mucous membranes. It is caused by mutations in the COL7A1 gene, which is responsible for producing type VII collagen, a protein that helps form the anchoring fibrils that attach the epidermis to the dermis. People with AR-GDEB-IF experience recurrent blistering of the skin and mucous membranes, which can lead to scarring and disfigurement. They may also experience nail dystrophy, alopecia, and milia. Treatment is supportive and may include wound care, pain management, and nutritional support.