Autosomal dominant otospondylomegaepiphyseal dysplasia (AD-OSMED) is a rare genetic disorder that affects the development of bones and cartilage in the body. It is characterized by hearing loss, short stature, and skeletal abnormalities. The hearing loss is usually progressive and can lead to deafness. Other features of the disorder include a short neck, a small jaw, and a flattened face. The skeletal abnormalities can include a shortening of the long bones, a narrowing of the spinal canal, and a flattening of the vertebrae.