Autosomal dominant optic atrophy, classic form (ADOA-CF) is a rare inherited disorder that affects the optic nerve, which carries visual information from the eye to the brain. It is characterized by progressive vision loss, usually beginning in childhood or adolescence. Symptoms may include decreased visual acuity, color vision deficits, and night blindness. In some cases, the disorder may also cause nystagmus (involuntary eye movements) and strabismus (misalignment of the eyes). ADOA-CF is caused by mutations in the OPA1 gene and is inherited in an autosomal dominant pattern.