Autosomal dominant Kenny-Caffey syndrome is a rare genetic disorder characterized by short stature, delayed bone development, and abnormally small bones in the hands and feet. It is caused by a mutation in the TBCE gene, which is responsible for the production of a protein involved in bone development. Symptoms of the disorder can vary from person to person, but may include short stature, delayed bone development, abnormally small bones in the hands and feet, and vision problems.

The symptoms of Autosomal dominant Kenny-Caffey syndrome include:

-Delayed growth and development
-Short stature
-Thin bones
-Large head
-Widely spaced eyes
-Widely spaced teeth
-High forehead
-Widely spaced nipples
-Delayed closure of the fontanels
-Delayed eruption of teeth
-Delayed puberty
-Intellectual disability
-Seizures
-Hearing loss
-Vision problems
-Abnormalities of the hands and feet
-Abnormalities of the heart and kidneys

The cause of Autosomal dominant Kenny-Caffey syndrome is unknown. It is believed to be caused by a mutation in the TBCE gene, which is responsible for the production of a protein called tubulin-specific chaperone E. This protein is involved in the formation of microtubules, which are essential for the normal development of bones and other tissues.

1. Growth hormone therapy: Growth hormone therapy is used to help promote growth and development in children with Kenny-Caffey Syndrome.

2. Physical therapy: Physical therapy can help improve muscle strength and coordination, as well as help with balance and posture.

3. Occupational therapy: Occupational therapy can help with activities of daily living, such as dressing, eating, and writing.

4. Speech therapy: Speech therapy can help with communication and language development.

5. Surgery: Surgery may be necessary to correct skeletal abnormalities, such as bowed legs or a curved spine.

6. Medications: Medications may be prescribed to help with pain, seizures, or other symptoms.

1. Family history: Autosomal dominant Kenny-Caffey syndrome is an inherited disorder, so having a family history of the condition increases the risk of developing it.

2. Age: The condition is more common in children and young adults.

3. Gender: Autosomal dominant Kenny-Caffey syndrome is more common in males than females.

There is no cure for Autosomal dominant Kenny-Caffey syndrome. Treatment focuses on managing the symptoms, which may include physical therapy, occupational therapy, speech therapy, and medications to help with pain, seizures, and other symptoms.