Autosomal dominant coarctation of aorta is a genetic disorder that affects the aorta, the main artery that carries blood from the heart to the rest of the body. It is caused by a narrowing of the aorta, which can lead to high blood pressure, heart failure, and other complications. It is inherited in an autosomal dominant pattern, meaning that a single copy of the mutated gene is enough to cause the disorder.

The most common symptom of autosomal dominant coarctation of the aorta is High blood pressure in the arms and low blood pressure in the legs. Other symptoms may include chest pain, shortness of breath, fatigue, and dizziness. In some cases, a heart murmur may be heard.

The exact cause of autosomal dominant coarctation of the aorta is unknown. However, it is believed to be caused by a combination of genetic and environmental factors. Genetic factors may include mutations in certain genes, such as the ELN gene, which is involved in the development of the aorta. Environmental factors may include maternal smoking, alcohol consumption, and certain medications taken during pregnancy.

1. Balloon angioplasty: This procedure involves inserting a balloon-tipped catheter into the narrowed area of the aorta and inflating the balloon to widen the area.

2. Surgery: This procedure involves surgically widening the narrowed area of the aorta.

3. Stent placement: This procedure involves inserting a metal stent into the narrowed area of the aorta to keep it open.

4. Medication: Medications such as beta-blockers and ACE inhibitors may be prescribed to help reduce the risk of complications associated with coarctation of the aorta.

1. Family history of Autosomal dominant coarctation of aorta
2. Turner Syndrome
3. Marfan Syndrome
4. Bicuspid aortic valve
5. Hypertension
6. Abnormal aortic arch
7. Abnormal aortic root
8. Abnormal aortic valve
9. Abnormal coronary arteries
10. Abnormal mitral valve

Yes, there is a cure for Autosomal dominant coarctation of aorta. Treatment typically involves surgery to repair the narrowed section of the aorta. Medications may also be prescribed to help manage symptoms and reduce the risk of complications.