Treatment for antenatal multiminicore disease with arthrogryposis multiplex congenita (AMC) is focused on managing the symptoms and complications associated with the condition. Treatment may include physical therapy, occupational therapy, orthopedic surgery, and bracing. Physical therapy can help improve range of motion, strength, and coordination. Occupational therapy can help with activities of daily living, such as dressing, eating, and bathing. Orthopedic surgery may be necessary to correct joint deformities and improve range of motion. Bracing may be used to help support weakened muscles and joints. In some cases, medications may be prescribed to help manage muscle spasms.