Unfortunately, there is no known cure for Adult familial nephronophthisis-spastic quadriparesia syndrome. Treatment focuses on managing the symptoms and complications of the condition. This may include physical therapy, occupational therapy, speech therapy, and medications to help manage muscle spasms and pain. In some cases, surgery may be recommended to help improve mobility. Additionally, it is important to maintain a healthy lifestyle, including a balanced diet and regular exercise, to help manage symptoms and improve overall health.