Acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) are both types of blood cancers that can be caused by exposure to radiation. Radiation can damage the DNA of cells, leading to mutations that can cause cancer. People who have been exposed to high levels of radiation, such as those who have had radiation therapy for cancer, are at an increased risk of developing AML or MDS.

Symptoms of Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS) related to radiation exposure may include:

-Fatigue
-Fever
-Weight loss
-Shortness of breath
-Easy bruising or bleeding
-Frequent infections
-Enlarged lymph nodes, spleen, or liver
-Bone or joint pain
-Pale skin
-Abnormal bleeding from the nose, gums, or rectum
-Abnormal bruising
-Night sweats
-Loss of appetite
-Nausea and vomiting
-Abnormal liver function tests
-Abnormal blood counts, including low red blood cell counts (anemia) and low platelet counts (thrombocytopenia)

1. Exposure to high doses of radiation, such as radiation therapy for cancer, can increase the risk of developing acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).

2. Exposure to low doses of radiation, such as from medical imaging tests, may also increase the risk of developing AML and MDS.

3. Exposure to certain chemicals, such as benzene, can increase the risk of developing AML and MDS.

4. Exposure to certain viruses, such as human T-cell leukemia virus-1 (HTLV-1), can increase the risk of developing AML and MDS.

5. Having certain genetic conditions, such as Down syndrome, can increase the risk of developing AML and MDS.

Treatments for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS) related to radiation include:

1. Chemotherapy: Chemotherapy is the most common treatment for AML and MDS related to radiation. It involves using drugs to kill cancer cells.

2. Targeted Therapy: Targeted therapy is a type of treatment that uses drugs to target specific molecules involved in the growth and spread of cancer cells.

3. Stem Cell Transplant: A stem cell transplant is a procedure in which healthy stem cells are transplanted into the body to replace damaged or destroyed cells.

4. Radiation Therapy: Radiation therapy is a type of treatment that uses high-energy beams of radiation to kill cancer cells.

5. Surgery: Surgery may be used to remove

1. Exposure to high doses of radiation, such as radiation therapy for cancer or radiation exposure from nuclear accidents.
2. Exposure to certain chemicals, such as benzene, which is found in gasoline and other petroleum products.
3. Exposure to certain viruses, such as human T-cell leukemia virus-1 (HTLV-1).
4. Having certain genetic disorders, such as Down syndrome or Fanconi anemia.
5. Having a family history of AML or MDS.
6. Being over the age of 60.
7. Having certain blood disorders, such as myeloproliferative disorders or myelodysplastic syndromes.
8. Having certain medical conditions, such as aplastic anemia or immune system disorders.

The treatment for Acute myeloid leukemia and myelodysplastic syndromes related to radiation depends on the type and stage of the disease. Treatment options may include chemotherapy, radiation therapy, stem cell transplant, targeted therapy, and supportive care. Medications used to treat these conditions may include hydroxyurea, decitabine, azacitidine, and lenalidomide.