The exact cause of acute fatty liver of pregnancy (AFLP) is unknown, but it is thought to be related to a combination of genetic, metabolic, and hormonal factors. Possible causes include:
- Genetic predisposition: Certain genetic mutations may increase the risk of developing AFLP.
- Metabolic abnormalities: Abnormalities in the metabolism of fatty acids may lead to an accumulation of fat in the liver.
- Hormonal imbalances: Hormonal imbalances, such as an increase in estrogen levels, may contribute to the development of AFLP.
- Nutritional deficiencies: Deficiencies in certain vitamins and minerals, such as vitamin E, may increase the risk of developing AFLP.
- Medications: Certain medications, such as corticosteroids, may increase the risk of developing AFLP.