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About Acropectoral syndrome

What is Acropectoral syndrome?

Acropectoral syndrome is a rare genetic disorder characterized by the presence of extra fingers and toes (polydactyly), as well as abnormalities of the chest wall and shoulder girdle. It is caused by a mutation in the HOXD13 gene. Symptoms may include webbing of the fingers and toes, underdeveloped or absent pectoral muscles, and a narrow chest. Treatment typically involves surgery to correct the physical abnormalities.

What are the symptoms of Acropectoral syndrome?

The symptoms of Acropectoral syndrome vary from person to person, but may include:

-Short stature
-Underdeveloped or absent pectoral muscles
-Underdeveloped or absent deltoid muscles
-Underdeveloped or absent biceps and triceps
-Underdeveloped or absent abdominal muscles
-Underdeveloped or absent shoulder blades
-Underdeveloped or absent clavicles
-Underdeveloped or absent sternum
-Underdeveloped or absent ribs
-Underdeveloped or absent scapulae
-Underdeveloped or absent humerus
-Underdeveloped or absent radius and ulna
-Underdeveloped or absent hands and feet
-Underdeveloped or absent fingers and toes
-Underdeveloped or absent nails
-Underdeveloped or absent facial features
-Underdeveloped or absent ears
-Underdeveloped or absent nose

What are the causes of Acropectoral syndrome?

Acropectoral syndrome is a rare genetic disorder caused by a mutation in the GJA1 gene. This gene is responsible for producing a protein called connexin 43, which is important for the development of the bones and muscles in the arms and legs. Mutations in this gene can lead to a variety of skeletal and muscular abnormalities, including acropectoral syndrome.

What are the treatments for Acropectoral syndrome?

The treatment for Acropectoral syndrome is typically focused on managing the symptoms and complications associated with the condition. Treatment may include physical therapy, occupational therapy, speech therapy, orthopedic surgery, and/or medications to help manage pain and other symptoms. Surgery may be necessary to correct any skeletal deformities or to improve joint mobility. In some cases, braces or splints may be used to help support the affected joints.

What are the risk factors for Acropectoral syndrome?

The exact cause of Acropectoral syndrome is unknown, but some risk factors may include:

• Genetic predisposition
• Exposure to certain environmental toxins
• Exposure to certain medications
• Maternal smoking during pregnancy
• Maternal alcohol consumption during pregnancy
• Maternal drug use during pregnancy
• Maternal diabetes during pregnancy
• Maternal obesity during pregnancy
• Maternal age over 35 years old
• Low birth weight
• Premature birth

Is there a cure/medications for Acropectoral syndrome?

At this time, there is no known cure for Acropectoral syndrome. However, there are medications that can be used to manage the symptoms associated with the condition. These medications may include muscle relaxants, anti-inflammatory drugs, and pain relievers. Additionally, physical therapy and occupational therapy may be recommended to help improve mobility and strength.