Acromegaly is a rare disorder caused by an excess of growth hormone in the body. It is usually caused by a benign tumor on the pituitary gland, which is located at the base of the brain. Symptoms of acromegaly include enlargement of the hands, feet, and facial features, as well as joint pain, headaches, and fatigue. If left untreated, acromegaly can lead to serious health complications, such as diabetes, heart disease, and high blood pressure. Treatment typically involves surgery to remove the tumor, as well as medications to reduce the amount of growth hormone in the body.