Acrofacial dysostosis, Rodriguez type is a rare genetic disorder characterized by facial abnormalities, skeletal malformations, and intellectual disability. It is caused by a mutation in the gene encoding the protein ROR2. Symptoms may include a wide-set eyes, a flat nasal bridge, a small lower jaw, and a cleft palate. Other features may include hearing loss, scoliosis, and short stature. Treatment is supportive and may include physical and occupational therapy, speech therapy, and special education.