The treatments for Acrocallosal syndrome vary depending on the individual and the severity of the condition. Generally, treatment focuses on managing the symptoms and complications associated with the condition. This may include physical therapy, occupational therapy, speech therapy, and nutritional support. Surgery may be necessary to correct any physical deformities or to improve the functioning of the digestive system. Medications may be prescribed to help control seizures, manage pain, and reduce inflammation. In some cases, genetic counseling may be recommended.