Acquired angioedema type 2 (AAE2) is a rare, inherited disorder that causes recurrent episodes of swelling in the face, tongue, and/or throat. It is caused by a deficiency of the C1-esterase inhibitor protein, which is responsible for regulating the activity of certain enzymes in the body. Symptoms of AAE2 can include swelling of the face, tongue, and/or throat, difficulty breathing, and abdominal pain. Treatment typically involves the use of medications to reduce the swelling and prevent future episodes.

The symptoms of Acquired Angioedema Type 2 (AACE2) include:

-Swelling of the face, lips, tongue, and throat
-Difficulty breathing
-Abdominal pain
-Nausea and vomiting
-Diarrhea
-Hives
-Itching
-Swelling of the hands and feet
-Joint pain
-Fatigue
-Fever

Acquired angioedema type 2 is caused by an autoimmune response, where the body produces antibodies that attack and damage the C1 inhibitor protein. This protein is responsible for controlling the activity of certain enzymes in the body that are involved in the inflammatory response. Common causes of acquired angioedema type 2 include certain medications, infections, and autoimmune diseases such as lupus and rheumatoid arthritis.

The main treatment for Acquired Angioedema Type 2 is the use of C1-inhibitor replacement therapy. This involves the intravenous administration of a purified form of C1-inhibitor, which is a protein that helps regulate the immune system. Other treatments may include antihistamines, corticosteroids, and immunosuppressants. In some cases, plasmapheresis (the removal of plasma from the blood) may be used to reduce the levels of C1-inhibitor in the blood.

1. Female gender
2. Age over 40
3. Family history of angioedema
4. Allergy to certain medications
5. Exposure to certain environmental triggers
6. Certain autoimmune diseases
7. Certain infections
8. Certain genetic mutations

Yes, there are medications available to treat Acquired Angioedema Type 2. These include medications such as C1-inhibitors, corticosteroids, and antihistamines. Additionally, some patients may benefit from immunosuppressive medications such as cyclosporine or rituximab.