Aceruloplasminemia is a rare genetic disorder that affects the body's ability to metabolize iron. It is caused by a mutation in the ceruloplasmin gene, which is responsible for producing the ceruloplasmin protein. This protein helps the body to store and transport iron, and without it, iron accumulates in the body's tissues and organs, leading to a variety of symptoms. Symptoms of aceruloplasminemia include vision problems, seizures, movement disorders, and cognitive impairment. Treatment typically involves iron chelation therapy and dietary modifications.