About Zygodactyly type 1

What is Zygodactyly type 1?

Zygodactyly type 1 is a rare genetic disorder characterized by the fusion of the second and third toes on each foot. It is caused by a mutation in the HOXD13 gene. Symptoms may include webbing between the toes, a wide gap between the first and second toes, and a wide gap between the fourth and fifth toes.

What are the symptoms of Zygodactyly type 1?

The symptoms of Zygodactyly type 1 include:

-Symmetrical, webbed fingers and toes
-Shortened or absent middle phalanges
-Shortened or absent distal phalanges
-Shortened or absent metacarpals
-Shortened or absent metatarsals
-Shortened or absent proximal phalanges
-Shortened or absent interphalangeal joints
-Shortened or absent thumb
-Shortened or absent big toe
-Shortened or absent fifth toe
-Shortened or absent fourth toe
-Shortened or absent third toe
-Shortened or absent second toe
-Shortened or absent first toe
-Shortened or absent nail beds
-Shortened or absent nail plates
-Shortened or absent creases in the palms of the hands
-Short

What are the causes of Zygodactyly type 1?

Zygodactyly type 1 is a rare genetic disorder caused by a mutation in the HOXD13 gene. This gene is responsible for the development of the hands and feet. The mutation can be inherited from a parent or can occur spontaneously.

What are the treatments for Zygodactyly type 1?

1. Surgery: Surgery is the most common treatment for zygodactyly type 1. The goal of surgery is to separate the fused digits and create a more normal appearance.

2. Physical Therapy: Physical therapy can help improve range of motion and strength in the affected digits.

3. Splinting: Splinting can help to maintain the position of the digits and prevent further fusion.

4. Occupational Therapy: Occupational therapy can help with activities of daily living and help the patient adapt to their condition.

5. Orthotics: Orthotics can help to provide support and stability to the affected digits.

What are the risk factors for Zygodactyly type 1?

1. Family history of Zygodactyly type 1
2. Maternal diabetes
3. Maternal obesity
4. Maternal smoking
5. Maternal alcohol consumption
6. Advanced maternal age
7. Exposure to certain medications during pregnancy
8. Exposure to certain environmental toxins during pregnancy

Is there a cure/medications for Zygodactyly type 1?

At this time, there is no known cure for Zygodactyly type 1. However, there are medications that can help manage the symptoms. These include anti-inflammatory medications, muscle relaxants, and physical therapy.