Wild type ATTR amyloidosis is a rare, inherited form of amyloidosis caused by a mutation in the transthyretin (TTR) gene. It is characterized by the buildup of abnormal proteins in the body's organs and tissues, leading to organ damage and other serious health problems. Symptoms of wild type ATTR amyloidosis can include fatigue, weight loss, peripheral neuropathy, carpal tunnel syndrome, and heart problems. Treatment options for wild type ATTR amyloidosis include medications, liver transplantation, and gene therapy.

The symptoms of Wild type ATTR amyloidosis vary depending on the organs affected, but may include:

-Fatigue

-Weight loss

-Muscle weakness

-Numbness or Tingling in the hands and feet

-Swelling in the legs and abdomen

-Shortness of breath

-Heart palpitations

-Carpal tunnel syndrome

-Diarrhea

-Difficulty swallowing

-Vision problems

-Cognitive decline

-Depression

-Anxiety

Wild type ATTR amyloidosis is caused by mutations in the transthyretin (TTR) gene. These mutations cause the TTR protein to misfold and form amyloid fibrils, which accumulate in the body's tissues and organs. This accumulation of amyloid fibrils can lead to organ damage and other symptoms.

The main treatments for Wild type ATTR amyloidosis are:

1. Liver transplantation: This is the most effective treatment for Wild type ATTR amyloidosis, as it can remove the source of the amyloid protein and stop the progression of the disease.

2. Medications: There are several medications that can be used to reduce the symptoms of Wild type ATTR amyloidosis, such as diuretics, ACE inhibitors, and statins.

3. Diet and lifestyle changes: Eating a healthy diet and exercising regularly can help reduce the symptoms of Wild type ATTR amyloidosis.

4. Stem cell transplantation: This is a newer treatment option that is being studied for Wild type ATTR amyloidosis. It involves transplanting healthy stem cells into the body to replace the

1. Age: Wild type ATTR amyloidosis is more common in people over the age of 65.

2. Gender: Wild type ATTR amyloidosis is more common in men than in women.

3. Family history: Wild type ATTR amyloidosis is more common in people with a family history of the disease.

4. Ethnicity: Wild type ATTR amyloidosis is more common in people of African, Caribbean, and Mediterranean descent.

5. Lifestyle: People who smoke, drink alcohol, or have a poor diet may be at an increased risk for developing Wild type ATTR amyloidosis.

Yes, there are treatments available for Wild type ATTR amyloidosis. These include medications such as tafamidis, diflunisal, and doxycycline, as well as liver transplantation. Additionally, supportive care such as dietary modifications, physical therapy, and lifestyle changes can help manage symptoms.