About Vogt-Koyanagi-Harada (VKH) Disease

What is Vogt-Koyanagi-Harada (VKH) Disease?

Vogt-Koyanagi-Harada (VKH) Disease is an autoimmune disorder that affects the eyes, skin, and inner ear. It is characterized by inflammation of the uvea, which is the middle layer of the eye, and can lead to vision loss. Symptoms include eye pain, redness, sensitivity to light, and vision loss. Treatment typically involves corticosteroids and immunosuppressants.

What are the symptoms of Vogt-Koyanagi-Harada (VKH) Disease?

The most common symptoms of Vogt-Koyanagi-Harada (VKH) Disease include:

-Uveitis (Inflammation of the middle layer of the eye)
-Hair loss
-Skin discoloration
-Hearing loss
-Headache
-Nausea
-Vomiting
-High blood pressure
-Eye pain
-Blurred vision
-Floaters
-Photophobia (sensitivity to light)
-Reduced vision

What are the causes of Vogt-Koyanagi-Harada (VKH) Disease?

The exact cause of Vogt-Koyanagi-Harada (VKH) Disease is unknown. However, it is believed to be an autoimmune disorder, meaning that the body's immune system mistakenly attacks healthy tissue. It is also thought to be triggered by certain environmental factors, such as exposure to ultraviolet light, certain infections, and certain medications.

What are the treatments for Vogt-Koyanagi-Harada (VKH) Disease?

1. Corticosteroid medications: Corticosteroids are the most commonly used treatment for VKH disease. They help reduce inflammation and can help improve vision.

2. Immunosuppressive medications: These medications help suppress the immune system and can help reduce inflammation.

3. Phototherapy: Phototherapy, or light therapy, can help reduce inflammation and improve vision.

4. Surgery: Surgery may be necessary to repair any damage to the eye caused by VKH disease.

5. Vitamins and supplements: Certain vitamins and supplements may help reduce inflammation and improve vision.

What are the risk factors for Vogt-Koyanagi-Harada (VKH) Disease?

1. Genetic predisposition: VKH is more common in certain ethnic groups, such as those of Asian, Hispanic, and African descent.

2. Sun exposure: VKH is more common in people who are exposed to more sunlight.

3. Age: VKH is more common in people between the ages of 20 and 50.

4. Gender: VKH is more common in women than in men.

5. Infections: Certain infections, such as tuberculosis, may increase the risk of VKH.

Is there a cure/medications for Vogt-Koyanagi-Harada (VKH) Disease?

Yes, there are treatments available for Vogt-Koyanagi-Harada (VKH) Disease. Treatment typically includes corticosteroid medications, such as prednisone, to reduce inflammation and suppress the immune system. Other medications, such as immunosuppressants, may also be prescribed to reduce the risk of flare-ups. In some cases, phototherapy may be used to reduce inflammation. Surgery may be necessary to repair any damage to the eye.