Ulnar-mammary syndrome is a rare genetic disorder that affects the development of the hands, arms, chest, and breasts. It is caused by a mutation in the TBX3 gene and is characterized by underdeveloped or absent thumbs, webbing of the fingers, and hypoplasia of the chest and breasts. Other features may include short stature, hearing loss, and heart defects.

The symptoms of Ulnar-mammary syndrome vary from person to person, but may include:

-Abnormal development of the hands and feet, including webbing of the fingers and toes, extra digits, and/or fused digits

-Abnormal development of the chest, including widely spaced nipples, extra nipples, and/or webbing of the chest

-Abnormal development of the face, including a broad, flat nose, a wide mouth, and/or a small chin

-Abnormal development of the ears, including low-set ears, cupped ears, and/or a small ear opening

-Abnormal development of the eyes, including droopy eyelids, small eyes, and/or a wide-set eyes

-Abnormal development of the head, including a Large head size and/or

Ulnar-mammary syndrome is a rare genetic disorder caused by a mutation in the TBX3 gene. This gene is responsible for the development of certain structures in the body, including the hands, arms, and chest. The mutation can be inherited from either parent or can occur spontaneously.

Treatment for Ulnar-mammary syndrome is typically focused on managing the symptoms and complications associated with the condition. Treatment may include physical therapy, occupational therapy, and/or speech therapy to help improve motor skills, communication, and daily living activities. Surgery may be recommended to correct any skeletal abnormalities or to release tight muscles. Orthopedic braces may be used to help support weakened joints. In some cases, medications may be prescribed to help manage pain and other symptoms.

1. Genetic mutation in the TBX3 gene
2. Family history of Ulnar-mammary syndrome
3. Maternal exposure to certain medications during pregnancy
4. Maternal diabetes
5. Maternal obesity
6. Maternal smoking during pregnancy

There is no known cure for Ulnar-mammary syndrome. However, there are medications that can help manage the symptoms. These include nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce inflammation, anticonvulsants to control seizures, and muscle relaxants to reduce muscle spasms. In some cases, physical therapy and occupational therapy may also be recommended.