Transient tyrosinemia of the newborn is a rare metabolic disorder that affects newborns. It is caused by a deficiency of the enzyme fumarylacetoacetate hydrolase (FAH), which is responsible for breaking down the amino acid tyrosine. Without this enzyme, tyrosine builds up in the body, leading to a variety of symptoms, including jaundice, poor feeding, vomiting, and lethargy. Treatment typically involves dietary changes and supplementation with tyrosine-degrading enzymes.

Transient tyrosinemia of the newborn is caused by a deficiency of the enzyme fumarylacetoacetate hydrolase (FAH). This enzyme is responsible for breaking down the amino acid tyrosine, which is found in many foods. Without this enzyme, tyrosine builds up in the body and can cause a variety of symptoms.

The primary treatment for transient tyrosinemia of the newborn is dietary restriction of tyrosine and phenylalanine. This means that the baby should be given a low-tyrosine and low-phenylalanine formula. In some cases, a low-protein diet may also be recommended. In addition, vitamin supplements may be prescribed to help the baby absorb the nutrients from the formula. In severe cases, medications such as Nitisinone may be prescribed to help reduce the levels of tyrosine and phenylalanine in the body.

1. Premature birth
2. Low birth weight
3. Maternal diabetes
4. Maternal obesity
5. Maternal smoking
6. Maternal alcohol consumption
7. Maternal use of certain medications, such as anticonvulsants or antibiotics
8. Family history of transient tyrosinemia of the newborn

Yes, there is a cure for Transient Tyrosinemia of the Newborn (TTN). Treatment involves a low-tyrosine and low-phenylalanine diet, as well as medications such as Nitisinone and 2-MP. Nitisinone helps to reduce the amount of tyrosine and phenylalanine in the body, while 2-MP helps to break down the tyrosine and phenylalanine that is already present. In some cases, a liver transplant may be necessary.