Thoracolumbosacral spina bifida cystica is a type of spina bifida, a birth defect in which the spinal cord and its surrounding structures do not develop properly. It is a rare form of spina bifida that affects the lower back and can cause paralysis of the legs and bladder and bowel control problems. It is usually diagnosed at birth and can be treated with surgery.

The symptoms of Thoracolumbosacral spina bifida cystica can vary depending on the severity of the condition. Common symptoms include:

- Weakness or Paralysis of the lower limbs
- Abnormal curvature of the spine
- Abnormal positioning of the hips and legs
- Abnormal gait
- Urinary and/or bowel incontinence
- Abnormal sensation in the lower limbs
- Pain in the lower back or legs
- Abnormal development of the spinal cord and/or vertebrae
- Abnormal development of the ribs and/or sternum

Thoracolumbosacral spina bifida cystica is a rare congenital condition caused by a defect in the development of the neural tube during the first trimester of pregnancy. It is believed to be caused by a combination of genetic and environmental factors, such as maternal nutrition, exposure to certain medications, and certain infections.

The treatments for thoracolumbosacral spina bifida cystica depend on the severity of the condition. Generally, treatment may include surgery to close the spinal defect, physical therapy to help improve mobility, medications to reduce pain and inflammation, and bracing to help support the spine. In some cases, a shunt may be placed to help drain excess fluid from the spinal cord. In severe cases, a spinal fusion may be necessary to stabilize the spine.

1. Family history of neural tube defects
2. Maternal diabetes
3. Maternal obesity
4. Maternal use of certain medications, such as anticonvulsants, during pregnancy
5. Maternal exposure to certain environmental toxins, such as pesticides
6. Maternal folic acid deficiency
7. Maternal age over 35
8. Low socioeconomic status

There is no cure for thoracolumbosacral spina bifida cystica, but there are medications that can help manage the symptoms. These medications include pain relievers, muscle relaxants, and anticonvulsants. Surgery may also be recommended to correct any structural deformities or to relieve pressure on the spinal cord.