Temple-Baraitser syndrome is a rare genetic disorder characterized by intellectual disability, seizures, and facial abnormalities. It is caused by a mutation in the ZFHX3 gene. Symptoms may include delayed development, intellectual disability, seizures, facial abnormalities, and skeletal abnormalities.

The symptoms of Temple-Baraitser syndrome vary from person to person, but may include:

-Developmental delay
-Intellectual disability
-Seizures
-Movement disorders
-Behavioral problems
-Speech and language delays
-Growth delays
-Feeding difficulties
-Hearing loss
-Vision problems
-Heart defects
-Kidney abnormalities
-Skeletal abnormalities
-Skin abnormalities

Temple-Baraitser syndrome is a rare genetic disorder caused by mutations in the ZNF41 gene. The exact cause of the mutations is unknown, but they are believed to be inherited in an autosomal dominant pattern.

Currently, there is no known cure for Temple-Baraitser syndrome. Treatment focuses on managing the symptoms and complications associated with the condition. This may include physical therapy, occupational therapy, speech therapy, and medications to help manage seizures, muscle spasms, and other symptoms. Surgery may be recommended to correct any physical deformities or to help improve mobility. Additionally, genetic counseling may be recommended for families affected by the condition.

The primary risk factor for Temple-Baraitser syndrome is having a parent who carries a mutation in the ZNF41 gene. Other risk factors include having a family history of the condition, being of Ashkenazi Jewish descent, and having a parent with a balanced chromosomal translocation involving chromosome 1.

At this time, there is no known cure for Temple-Baraitser Syndrome. However, there are medications that can help manage some of the symptoms associated with the condition. These include medications to help with seizures, muscle spasms, and behavioral issues. Additionally, physical and occupational therapy can help improve motor skills and communication.