About Subepithelial mucinous corneal dystrophy

What is Subepithelial mucinous corneal dystrophy?

Subepithelial mucinous corneal dystrophy is a rare, inherited disorder of the cornea, the clear outer layer of the eye. It is characterized by the accumulation of mucin, a thick, jelly-like substance, beneath the epithelium, the outermost layer of the cornea. This accumulation causes the cornea to become cloudy and distorted, leading to decreased vision. Treatment typically involves the use of lubricating eye drops and, in some cases, corneal transplantation.

What are the symptoms of Subepithelial mucinous corneal dystrophy?

The most common symptom of Subepithelial mucinous corneal dystrophy is blurred vision. Other symptoms may include:

-Halos around lights

-Sensitivity to light

-Eye irritation

-Pain

-Redness

-Tearing

-Decreased vision

-Corneal opacities (cloudy areas on the cornea)

What are the causes of Subepithelial mucinous corneal dystrophy?

Subepithelial mucinous corneal dystrophy is a rare, inherited disorder caused by mutations in the TACSTD2 gene. This gene is responsible for producing a protein called mucin-2, which is found in the cornea. Mutations in this gene can lead to the accumulation of mucin-2 in the cornea, resulting in the formation of a thick, cloudy layer on the surface of the eye. This layer can cause vision problems, including blurred vision, glare, and halos around lights.

What are the treatments for Subepithelial mucinous corneal dystrophy?

1. Corneal transplantation: This is the most effective treatment for Subepithelial mucinous corneal dystrophy. It involves replacing the affected corneal tissue with healthy donor tissue.

2. Phototherapeutic keratectomy (PTK): This procedure uses a laser to remove the abnormal tissue from the cornea.

3. Corneal collagen cross-linking: This procedure strengthens the cornea by increasing the number of collagen fibers in the cornea.

4. Topical medications: These medications can help reduce inflammation and improve vision.

5. Intacs: These are small plastic rings that are inserted into the cornea to help reshape it and improve vision.

What are the risk factors for Subepithelial mucinous corneal dystrophy?

1. Age: Subepithelial mucinous corneal dystrophy is most commonly seen in adults over the age of 40.

2. Gender: Women are more likely to be affected than men.

3. Genetics: Subepithelial mucinous corneal dystrophy is an inherited condition, and is caused by a mutation in the TGFBI gene.

4. Sun exposure: Prolonged exposure to ultraviolet light from the sun may increase the risk of developing Subepithelial mucinous corneal dystrophy.

Is there a cure/medications for Subepithelial mucinous corneal dystrophy?

At this time, there is no known cure for Subepithelial mucinous corneal dystrophy. However, there are medications that can be used to manage the symptoms. These include topical lubricants, anti-inflammatory medications, and corticosteroids. In some cases, surgery may be recommended to improve vision.