Sub-cortical nodular heterotopia is a rare neurological disorder that is caused by an abnormality in the migration of neurons during fetal development. It is characterized by the presence of nodules of neurons in the wrong place in the brain, usually in the sub-cortical white matter. Symptoms can include seizures, intellectual disability, and motor and language delays.

The symptoms of Sub-cortical nodular heterotopia vary depending on the severity of the condition. Common symptoms include seizures, developmental delays, intellectual disability, and movement disorders. Other symptoms may include speech and language delays, behavioral problems, and vision and hearing problems.

Sub-cortical nodular heterotopia is a rare neurological disorder caused by a genetic mutation. It is caused by a mutation in the Filamin A gene, which is responsible for the development of the brain. Other causes of Sub-cortical nodular heterotopia include chromosomal abnormalities, such as trisomy 13, and environmental factors, such as exposure to certain toxins or drugs during pregnancy.

1. Surgery: Surgery is the most common treatment for sub-cortical nodular heterotopia. The goal of surgery is to remove the abnormal tissue and reduce the risk of seizures.

2. Medication: Anti-seizure medications may be prescribed to help reduce the frequency and severity of seizures.

3. Dietary Changes: Dietary changes may be recommended to help reduce the risk of seizures. This may include avoiding certain foods or eating a specific diet.

4. Physical Therapy: Physical therapy may be recommended to help improve muscle strength and coordination.

5. Occupational Therapy: Occupational therapy may be recommended to help improve daily functioning and independence.

6. Speech Therapy: Speech therapy may be recommended to help improve communication skills.

1. Mutations in the Filamin A (FLNA) gene
2. X-linked inheritance
3. Family history of Sub-cortical nodular heterotopia
4. Maternal exposure to alcohol or drugs during pregnancy
5. Maternal diabetes
6. Maternal infection during pregnancy
7. Low birth weight
8. Premature birth

At this time, there is no known cure for sub-cortical nodular heterotopia. However, medications such as anticonvulsants and anti-seizure medications may be used to help manage the symptoms associated with this condition. Additionally, physical and occupational therapy may be beneficial in helping to improve motor skills and coordination.