Spinocerebellar ataxia type 11 (SCA11) is a rare, inherited neurological disorder that affects the cerebellum, a part of the brain that controls movement and coordination. It is caused by a mutation in the ATXN11 gene, which is responsible for producing a protein called ataxin-11. Symptoms of SCA11 include difficulty walking, balance problems, slurred speech, and difficulty with fine motor skills. In some cases, people with SCA11 may also experience seizures, dementia, and vision problems.

The symptoms of Spinocerebellar Ataxia type 11 (SCA11) vary from person to person, but may include:

• Unsteady gait

• Loss of coordination

• Difficulty with fine motor skills

• Slurred speech

• Muscle weakness

• Tremors

• Abnormal eye movements

• Difficulty swallowing

• Cognitive impairment

• Loss of balance

• Fatigue

• Depression

• Anxiety

Spinocerebellar ataxia type 11 (SCA11) is caused by a mutation in the ATXN11 gene. This gene provides instructions for making a protein called ataxin-11, which is involved in the development and maintenance of nerve cells in the brain and spinal cord. Mutations in the ATXN11 gene lead to the production of an abnormally short, nonfunctional version of the ataxin-11 protein. This abnormal protein disrupts the normal function of nerve cells, leading to the signs and symptoms of SCA11.

1. Physical therapy: Physical therapy can help improve balance, coordination, and strength. It can also help with activities of daily living, such as walking, dressing, and eating.

2. Occupational therapy: Occupational therapy can help with activities of daily living, such as dressing, eating, and writing.

3. Speech therapy: Speech therapy can help with communication and swallowing difficulties.

4. Medications: Medications can help reduce symptoms, such as tremor, muscle spasms, and difficulty walking.

5. Surgery: Surgery may be recommended in some cases to help improve balance and coordination.

6. Assistive devices: Assistive devices, such as canes, walkers, and wheelchairs, can help with mobility.

7. Nutritional counseling: Nutritional counseling can help ensure that you are

1. Age: SCA11 is most commonly diagnosed in individuals between the ages of 30 and 50.

2. Family history: SCA11 is an inherited disorder, so having a family history of the condition increases the risk of developing it.

3. Ethnicity: SCA11 is more common in individuals of Ashkenazi Jewish descent.

4. Genetic mutation: SCA11 is caused by a mutation in the ATXN11 gene. Individuals with this mutation are at an increased risk of developing the condition.

At this time, there is no cure for Spinocerebellar ataxia type 11 (SCA11). However, there are medications that can help manage the symptoms of SCA11, such as medications to help with balance, coordination, and muscle control. Additionally, physical and occupational therapy can help improve mobility and coordination.