Smallpox is an infectious disease caused by the variola virus. It is characterized by a fever and a distinctive, bumpy rash. Smallpox was once a common and deadly disease, but it has been eradicated worldwide through vaccination.

The symptoms of smallpox include a high fever, fatigue, headache, and backache. A few days after the Fever begins, a rash appears on the face and spreads to the arms, legs, and trunk. The rash starts with flat red spots that develop into raised bumps filled with a clear fluid. The bumps eventually turn into pus-filled Blisters that crust over and scab. Other symptoms may include vomiting, diarrhea, and abdominal pain.

Smallpox is caused by the variola virus, a member of the orthopoxvirus family. It is spread through contact with an infected person, either through direct contact or through the air when an infected person coughs or sneezes.

The only treatment for smallpox is vaccination. Vaccination with the smallpox vaccine (vaccinia) can prevent smallpox if given before or shortly after exposure to the virus. Vaccination can also reduce the severity of the disease if given within 3-5 days after exposure. In addition, supportive care such as fluids, antibiotics, and pain relief can help reduce the severity of the illness.

1. Living in or traveling to an area where smallpox is present.
2. Having a weakened immune system due to HIV/AIDS, cancer, or other conditions.
3. Working in a laboratory with smallpox virus.
4. Having close contact with someone who has smallpox.
5. Being born before 1972, when the smallpox vaccine was discontinued in the United States.

Smallpox has been eradicated, so there is no need for a cure or medications. Vaccination is the only way to prevent smallpox.