Short tarsus-absence of lower eyelashes syndrome is a rare genetic disorder characterized by the absence of lower eyelashes, a shortening of the tarsal plate (the lower eyelid), and a variety of other eye abnormalities. It is caused by a mutation in the FOXC2 gene. Symptoms may include drooping of the lower eyelids, tearing, and sensitivity to light. Treatment typically involves the use of artificial tears and lubricating ointments.

The primary symptom of Short tarsus-absence of lower eyelashes syndrome is the absence of lower eyelashes. Other symptoms may include short tarsus (the lower part of the eye socket), sparse eyebrows, and a wide nasal bridge. In some cases, individuals may also have a small lower jaw, a cleft palate, and/or hearing loss.

Short tarsus-absence of lower eyelashes syndrome is a rare genetic disorder caused by mutations in the FOXC2 gene. This gene is responsible for the development of the eyelids and the lower eyelashes. Mutations in this gene can lead to the absence of lower eyelashes, as well as a shortening of the tarsal plate, which is the structure that supports the eyelids. Other symptoms associated with this disorder include ptosis (drooping of the upper eyelid), strabismus (crossed eyes), and blepharophimosis (narrowing of the eyelids).

Unfortunately, there is no known cure for Short tarsus-absence of lower eyelashes syndrome. Treatment is focused on managing the symptoms and preventing complications. This may include:

• Regular eye exams to monitor for any changes in vision
• Artificial tears to keep the eyes moist
• Wearing sunglasses to protect the eyes from the sun
• Wearing a wide-brimmed hat to protect the eyes from the sun
• Using lubricating eye drops to reduce dryness
• Using lubricating ointments at night to reduce dryness
• Using a humidifier to reduce dryness in the air
• Wearing protective eyewear when engaging in activities that may cause eye injury
• Using a warm compress to reduce inflammation
• Avoiding rubbing or touching the eyes
• Avoiding eye makeup and other products that may irritate

The exact cause of Short tarsus-absence of lower eyelashes syndrome is unknown. However, some risk factors may increase the likelihood of developing the condition, including:

• Family history: Short tarsus-absence of lower eyelashes syndrome is thought to be inherited in an autosomal recessive pattern, which means that both parents must carry the gene for a child to be affected.

• Ethnicity: Short tarsus-absence of lower eyelashes syndrome is more common in certain ethnic groups, such as those of Middle Eastern or North African descent.

At this time, there is no known cure or medications for Short tarsus-absence of lower eyelashes syndrome. Treatment is focused on managing the symptoms and preventing complications. This may include using artificial tears to keep the eyes moist, using lubricating ointments, and wearing protective eyewear to prevent eye injury. In some cases, eyelash transplants may be recommended to help improve the appearance of the eyes.