About Pseudomyxoma Peritonei

What is Pseudomyxoma Peritonei?

Pseudomyxoma Peritonei (PMP) is a rare form of cancer that affects the abdominal cavity. It is caused by the spread of mucinous tumors from the appendix to the abdominal cavity. Symptoms of PMP include abdominal pain, bloating, nausea, and vomiting. Treatment typically involves surgery to remove the tumor and any affected organs, followed by chemotherapy and/or radiation therapy.

What are the symptoms of Pseudomyxoma Peritonei?

The most common symptoms of Pseudomyxoma Peritonei are abdominal pain, abdominal swelling, nausea, vomiting, and constipation. Other symptoms may include weight loss, fatigue, and fever. In some cases, the disease may cause a mass or lump to form in the abdomen.

What are the causes of Pseudomyxoma Peritonei?

Pseudomyxoma Peritonei (PMP) is a rare form of cancer that affects the abdominal cavity. It is caused by the abnormal growth of cells in the appendix, which can spread to other parts of the abdomen. The exact cause of PMP is unknown, but it is believed to be related to a mutation in the APC gene. This gene is responsible for controlling cell growth and division, and when it is mutated, it can lead to the abnormal growth of cells. Other possible causes of PMP include genetic predisposition, environmental factors, and previous abdominal surgery.

What are the treatments for Pseudomyxoma Peritonei?

The main treatments for Pseudomyxoma Peritonei are cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). Cytoreductive surgery is a major operation that involves removing as much of the tumor as possible. HIPEC is a procedure that involves delivering heated chemotherapy directly to the abdomen during surgery. Other treatments may include radiation therapy, systemic chemotherapy, and targeted therapy.

What are the risk factors for Pseudomyxoma Peritonei?

The exact cause of pseudomyxoma peritonei is unknown, but it is believed to be related to the spread of mucinous tumors from the appendix. Risk factors for pseudomyxoma peritonei include:

• Previous appendectomy
• Age (most commonly occurs in people between the ages of 40 and 60)
• Gender (more common in women)
• Family history of pseudomyxoma peritonei
• Genetic mutations, such as those in the APC gene
• Exposure to certain chemicals, such as asbestos

Is there a cure/medications for Pseudomyxoma Peritonei?

Yes, there are treatments available for Pseudomyxoma Peritonei. These include surgery, chemotherapy, and intraperitoneal chemotherapy. Depending on the individual case, a combination of these treatments may be used.