Propylthiouracil embryofetopathy is a rare condition caused by the use of the drug propylthiouracil (PTU) during pregnancy. It is characterized by a variety of birth defects, including facial abnormalities, heart defects, and intellectual disability. The condition is thought to be caused by the drug's interference with the normal development of the fetus.

The symptoms of Propylthiouracil embryofetopathy (PTU embryofetopathy) vary depending on the severity of the condition. Common symptoms include:

-Growth retardation
-Developmental delay
-Facial dysmorphism
-Cardiac defects
-Cleft lip/palate
-Craniosynostosis
-Cerebral atrophy
-Seizures
-Hearing loss
-Hypothyroidism
-Abnormalities of the eyes, ears, and nose
-Abnormalities of the hands and feet
-Abnormalities of the genitalia
-Abnormalities of the urinary tract
-Abnormalities of the gastrointestinal tract

Propylthiouracil embryofetopathy is a rare condition caused by the use of the drug propylthiouracil (PTU) during pregnancy. PTU is a medication used to treat hyperthyroidism, an overactive thyroid. The condition is caused by the drug crossing the placenta and interfering with the normal development of the fetus. It can cause a range of birth defects, including heart defects, facial abnormalities, and intellectual disability.

1. Close monitoring of the baby's growth and development.

2. Treatment with thyroid hormone replacement therapy.

3. Treatment with antithyroid medications such as propylthiouracil or methimazole.

4. Surgery to remove the thyroid gland.

5. Dietary modifications to reduce the amount of iodine in the diet.

6. Vitamin and mineral supplementation.

7. Physical therapy to help with any developmental delays.

8. Speech therapy to help with any speech delays.

9. Occupational therapy to help with any motor delays.

10. Psychological counseling to help with any emotional issues.

1. Maternal use of Propylthiouracil (PTU) during the first trimester of pregnancy.

2. High doses of PTU during pregnancy.

3. Long-term use of PTU prior to pregnancy.

4. Maternal age over 35.

5. Maternal smoking.

6. Maternal alcohol consumption.

7. Maternal diabetes.

8. Maternal thyroid disease.

9. Maternal obesity.

10. Maternal hypertension.

At this time, there is no known cure for Propylthiouracil embryofetopathy. However, there are medications that can be used to manage the symptoms of the condition. These medications include antithyroid drugs, such as propylthiouracil, methimazole, and carbimazole, as well as corticosteroids and beta-blockers. Additionally, some patients may benefit from dietary changes, such as avoiding foods high in iodine, and supplementing with selenium.