Progressive pseudorheumatoid arthropathy of childhood (PPAC) is a rare, non-inflammatory, non-progressive joint disorder that affects children. It is characterized by joint pain, stiffness, and swelling, as well as a decrease in range of motion. It is thought to be caused by an abnormal immune response to an unknown trigger. Treatment typically involves physical therapy, medications, and lifestyle modifications.

The symptoms of Progressive pseudorheumatoid arthropathy of childhood (PPAC) vary from person to person, but may include:

• Joint Pain and swelling
• Stiffness
• Limitation of movement
• Muscle weakness
• Fatigue
• Fever
• Weight loss
• Anemia
• Abnormal blood tests
• Skin rash
• Eye inflammation
• Abnormal growth of bones and joints

The exact cause of progressive pseudorheumatoid arthropathy of childhood (PPAC) is unknown. However, some researchers believe that it may be caused by an autoimmune disorder, genetic factors, or a combination of both. Other possible causes include infections, environmental factors, and certain medications.

Treatment for progressive pseudorheumatoid arthropathy of childhood typically involves a combination of medications, physical therapy, and lifestyle modifications. Medications may include nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce inflammation and pain, corticosteroids to reduce inflammation, and disease-modifying antirheumatic drugs (DMARDs) to slow the progression of the disease. Physical therapy can help improve joint mobility and strength, while lifestyle modifications such as avoiding activities that put stress on the joints and maintaining a healthy weight can help reduce symptoms. In some cases, surgery may be necessary to correct joint deformities.

1. Age: Progressive pseudorheumatoid arthropathy of childhood is most commonly seen in children between the ages of 2 and 10 years old.

2. Gender: Girls are more likely to be affected than boys.

3. Genetics: There is a genetic component to the condition, as it is more common in certain families.

4. Immune system: Children with weakened immune systems are more likely to develop progressive pseudorheumatoid arthropathy of childhood.

5. Environmental factors: Exposure to certain environmental toxins or allergens may increase the risk of developing the condition.

At this time, there is no known cure for progressive pseudorheumatoid arthropathy of childhood. However, medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids may be used to reduce inflammation and pain. Physical therapy and occupational therapy may also be recommended to help maintain joint mobility and strength.