Primary megaureter, adult-onset form is a rare condition in which the ureter (the tube that carries urine from the kidney to the bladder) becomes abnormally enlarged. This condition can cause pain, difficulty urinating, and an increased risk of urinary tract infections. It is usually caused by a blockage in the ureter, which can be caused by a number of factors, including scarring, tumors, or an enlarged prostate. Treatment typically involves medications to reduce inflammation and pain, as well as surgery to remove the blockage.

The symptoms of Primary megaureter, adult-onset form may include:

-Pain in the lower abdomen or flank
-Frequent and/or painful urination
-Blood in the urine
-Urinary tract infections
-Incontinence
-Urine leakage
-Difficulty starting or stopping the flow of urine
-Weak or slow urinary stream
-Frequent urination at night (nocturia)
-Abdominal or flank mass
-Abdominal or flank pain
-Fever
-Nausea and vomiting

The exact cause of primary megaureter, adult-onset form is unknown. However, it is believed to be related to a combination of factors, including genetic predisposition, anatomical abnormalities, and environmental factors. Possible causes include:

• Congenital abnormalities of the ureter, such as an abnormally narrow ureter or a ureter that is too short.

• Blockage of the ureter due to a kidney stone, tumor, or other obstruction.

• Infection of the urinary tract, such as a urinary tract infection (UTI).

• Injury to the ureter due to trauma or surgery.

• Abnormalities of the bladder, such as an overactive bladder or bladder outlet obstruction.

• Hormonal imbalances, such as an overproduction of the hormone

1. Antibiotics: Antibiotics may be prescribed to treat any underlying infection that may be causing the primary megaureter.

2. Surgery: Surgery may be necessary to correct the obstruction and restore normal urine flow. This may involve widening the ureter, removing any obstructions, or reconstructing the ureter.

3. Medications: Medications may be prescribed to relax the muscles of the ureter and reduce spasms.

4. Dietary changes: Dietary changes may be recommended to reduce the amount of acid in the urine and reduce the risk of infection.

5. Ureteral stent: A ureteral stent may be placed to keep the ureter open and allow urine to flow freely.

1. Previous urinary tract infection
2. Abnormalities of the urinary tract
3. Congenital anomalies of the urinary tract
4. Bladder outlet obstruction
5. Neurogenic bladder
6. Ureteral reflux
7. Pelvic surgery
8. Diabetes
9. Kidney stones
10. Prolonged use of a urinary catheter

Primary megaureter, adult-onset form is usually treated with a combination of medications and surgery. Medications used to treat this condition include alpha-blockers, which relax the muscles of the ureter and help reduce the pressure in the ureter, and diuretics, which help reduce the amount of urine produced. Surgery is usually recommended if medications are not effective. Surgery involves widening the ureter to allow urine to flow more freely. In some cases, a stent may be placed in the ureter to help keep it open.