Yes, there is a cure for Primary Hyperoxaluria Type 2. The treatment involves a liver transplant, which is the only known cure for this condition. Additionally, medications such as allopurinol and pyridoxine can be used to reduce the amount of oxalate in the body and help prevent further damage to the kidneys.

1. Genetic predisposition: Primary hyperoxaluria type 2 is caused by a mutation in the GRHPR gene, which is inherited in an autosomal recessive pattern.

2. Age: Primary hyperoxaluria type 2 is more common in children and young adults.

3. Gender: Primary hyperoxaluria type 2 is more common in males than females.

4. Ethnicity: Primary hyperoxaluria type 2 is more common in people of European descent.

The primary treatment for Primary Hyperoxaluria Type 2 is a liver transplant. This is the only known cure for the condition. Other treatments may include dietary changes, medications to reduce oxalate levels, and medications to reduce the risk of kidney stones. In some cases, dialysis may be necessary to help manage the condition.

Primary hyperoxaluria type 2 is caused by mutations in the GRHPR gene, which is responsible for producing an enzyme called glyoxylate reductase/hydroxypyruvate reductase. This enzyme helps to break down certain molecules in the body, including oxalate. When the enzyme is not functioning properly, oxalate levels in the body can become too high, leading to the development of primary hyperoxaluria type 2.

The symptoms of Primary Hyperoxaluria Type 2 (PH2) vary from person to person, but may include:

-Pain in the abdomen, back, or sides
-Frequent urination
-Cloudy or bloody urine
-Painful urination
-Kidney stones
-Nausea and vomiting
-Loss of appetite
-Weight loss
-Fatigue
-Weakness
-Itching
-Joint pain
-Muscle pain
-High levels of oxalate in the urine

Primary hyperoxaluria type 2 (PH2) is a rare inherited disorder that affects the liver and kidneys. It is caused by a deficiency of the enzyme alanine-glyoxylate aminotransferase (AGT). This enzyme is responsible for breaking down oxalate, a byproduct of metabolism. When AGT is deficient, oxalate builds up in the body and can cause kidney stones, kidney failure, and other serious health problems.