Parkinsonism with polyneuropathy is a rare neurological disorder characterized by the combination of Parkinson's disease-like symptoms and polyneuropathy, a condition in which multiple nerves throughout the body are damaged. Symptoms of Parkinsonism with polyneuropathy may include tremors, stiffness, difficulty walking, and balance problems. Other symptoms may include difficulty speaking, swallowing, and writing, as well as fatigue, depression, and cognitive impairment. Treatment typically involves medications to manage the symptoms, physical therapy, and lifestyle modifications.

The symptoms of Parkinsonism with polyneuropathy can vary depending on the severity of the condition, but may include:

- Muscle weakness
- Difficulty walking
- Loss of coordination
- Tremors
- Slowed movements
- Difficulty speaking
- Difficulty swallowing
- Loss of balance
- Fatigue
- Depression
- Anxiety
- Memory problems
- Urinary incontinence
- Constipation

1. Autoimmune disorders such as Guillain-Barre Syndrome
2. Vitamin B12 deficiency
3. Diabetes
4. Alcoholism
5. Certain medications
6. Toxins such as heavy metals
7. Infections such as HIV and Lyme disease
8. Hereditary conditions such as Charcot-Marie-Tooth disease

1. Medications: Medications such as levodopa, dopamine agonists, MAO-B inhibitors, and anticholinergics can be used to help manage the symptoms of Parkinsonism with polyneuropathy.

2. Physical Therapy: Physical therapy can help improve mobility and reduce pain associated with polyneuropathy.

3. Surgery: Surgery may be recommended in some cases to help reduce the symptoms of Parkinsonism with polyneuropathy.

4. Alternative Treatments: Alternative treatments such as acupuncture, massage, and yoga can help reduce pain and improve mobility.

5. Dietary Changes: Eating a healthy diet and avoiding certain foods can help reduce symptoms of Parkinsonism with polyneuropathy.

1. Advanced age
2. Diabetes
3. Vitamin B12 deficiency
4. Alcoholism
5. Exposure to certain toxins
6. Autoimmune disorders
7. Genetic predisposition
8. Certain medications
9. Infections, such as HIV or Lyme disease
10. Traumatic brain injury

There is no cure for Parkinsonism with polyneuropathy, but medications can help manage the symptoms. Common medications used to treat Parkinsonism with polyneuropathy include levodopa, dopamine agonists, anticholinergics, and amantadine. Other treatments such as physical therapy, occupational therapy, and speech therapy may also be recommended.