Non-syndromic unisquamosal craniosynostosis is a rare form of craniosynostosis, a condition in which the bones of the skull fuse together prematurely. In this condition, only one of the sutures (the squamosal suture) fuses prematurely, resulting in a misshapen skull. This condition is not associated with any other medical conditions or syndromes.

The symptoms of Non-syndromic unisquamosal craniosynostosis include:

-A triangular-shaped head
-A prominent forehead
-A flattened back of the head
-A wide-set eyes
-A flattened bridge of the nose
-A wide-set ears
-A wide-set jaw
-A short upper lip
-A high-arched palate
-A narrow roof of the mouth
-A small chin
-A small lower jaw
-A small lower face
-A small lower jaw
-A small lower face
-A small lower jaw
-A small lower face
-A small lower jaw
-A small lower face
-A small lower jaw
-A small lower face
-A small lower jaw
-A small lower face
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Non-syndromic unisquamosal craniosynostosis is a rare condition that is caused by a mutation in the FGFR2 gene. This gene is responsible for the production of a protein that helps regulate the growth of the skull. Mutations in this gene can cause the skull to fuse prematurely, resulting in unisquamosal craniosynostosis. Other causes of this condition include environmental factors, such as exposure to certain chemicals or radiation, and genetic factors, such as a family history of the condition.

1. Surgery: Surgery is the most common treatment for non-syndromic unisquamosal craniosynostosis. The goal of surgery is to reshape the skull and allow for normal brain growth. The surgery is usually done in infancy and involves removing the fused suture and reshaping the skull.

2. Orthotic Devices: Orthotic devices, such as helmets or headbands, may be used to help reshape the skull and protect the head from further deformity.

3. Physical Therapy: Physical therapy may be recommended to help improve range of motion and strength in the neck and head.

4. Medication: Medication may be prescribed to help reduce swelling and pain.

1. Family history of craniosynostosis
2. Maternal smoking during pregnancy
3. Maternal diabetes
4. Maternal obesity
5. Maternal use of certain medications during pregnancy
6. Low birth weight
7. Premature birth
8. Exposure to certain environmental toxins
9. Genetic mutations or chromosomal abnormalities

At this time, there is no cure for non-syndromic unisquamosal craniosynostosis. However, there are medications that can be used to help manage the symptoms associated with the condition. These medications include anti-inflammatory drugs, muscle relaxants, and pain medications. Surgery may also be recommended to correct the skull deformity and improve the appearance of the face.