Non-syndromic metopic craniosynostosis is a type of craniosynostosis, which is a condition in which the bones of the skull fuse together too early. In non-syndromic metopic craniosynostosis, the suture that runs down the middle of the forehead (the metopic suture) fuses too early, resulting in a triangular-shaped forehead. This condition is not associated with any other medical conditions or syndromes.

The most common symptoms of non-syndromic metopic craniosynostosis include:

-A triangular-shaped head
-A prominent forehead
-Wide-set eyes
-A narrow bridge of the nose
-A flattened area on the top of the head
-A raised or bulging area on the forehead
-A flattened area on the back of the head
-A wide or V-shaped hairline
-A wide or V-shaped groove in the forehead
-Delayed development of motor skills
-Delayed development of language skills
-Delayed development of social skills
-Delayed development of cognitive skills
-Seizures
-Vision problems
-Hearing problems
-Feeding problems

Non-syndromic metopic craniosynostosis is caused by a combination of genetic and environmental factors. Genetic factors include mutations in the FGFR2 gene, which is responsible for the development of the skull. Environmental factors include maternal smoking, alcohol consumption, and exposure to certain medications during pregnancy.

1. Endoscopic strip craniectomy: This is a minimally invasive procedure that involves removing a strip of bone from the metopic suture. This procedure is used to reduce the pressure on the brain and allow for normal growth of the skull.

2. Cranial vault remodeling: This procedure involves reshaping the skull to reduce the pressure on the brain and allow for normal growth.

3. Cranial osteotomy: This procedure involves cutting and reshaping the bones of the skull to reduce the pressure on the brain and allow for normal growth.

4. Cranial distraction: This procedure involves using a device to slowly separate the bones of the skull to reduce the pressure on the brain and allow for normal growth.

5. Surgery to release the sutures: This procedure involves cutting and releasing the sutures that are causing

1. Family history of craniosynostosis
2. Maternal diabetes
3. Maternal smoking
4. Maternal alcohol consumption
5. Low birth weight
6. Premature birth
7. Low socioeconomic status
8. Exposure to certain medications during pregnancy

At this time, there is no cure for non-syndromic metopic craniosynostosis. Treatment typically involves surgery to correct the shape of the skull and to allow for normal brain growth. Medications are not typically used to treat this condition.