About Non-syndromic bicoronal craniosynostosis

What is Non-syndromic bicoronal craniosynostosis?

Non-syndromic bicoronal craniosynostosis is a type of craniosynostosis, which is a condition in which the bones of the skull fuse together too early. In non-syndromic bicoronal craniosynostosis, the bones of the skull fuse together along the coronal sutures, which are the two sutures that run from ear to ear across the top of the head. This type of craniosynostosis is not associated with any other medical conditions or syndromes.

What are the symptoms of Non-syndromic bicoronal craniosynostosis?

The most common symptoms of non-syndromic bicoronal craniosynostosis include:
* A wide, flat head shape
* A prominent forehead
* A narrow, high-arched roof of the mouth
* A wide, flat bridge of the nose
* A wide, flat nasal bridge
* A wide, flat nasal tip
* A wide, flat philtrum
* A wide, flat upper lip
* A wide, flat lower lip
* A wide, flat chin
* A wide, flat jaw
* A wide, flat midface
* A wide, flat lower face
* A wide, flat skull base
* A wide, flat occiput
* A wide, flat temporal region
* A wide, flat parietal region
* A wide, flat frontal region
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What are the causes of Non-syndromic bicoronal craniosynostosis?

Non-syndromic bicoronal craniosynostosis is a rare condition that is caused by a combination of genetic and environmental factors. Genetic factors include mutations in certain genes that are involved in the development of the skull, such as FGFR2, TWIST1, and MSX2. Environmental factors include maternal smoking, alcohol consumption, and exposure to certain medications during pregnancy.

What are the treatments for Non-syndromic bicoronal craniosynostosis?

1. Endoscopic Strip Cranioplasty: This is a minimally invasive procedure that involves removing strips of bone from the fused sutures to allow for normal brain growth.

2. Cranial Vault Remodeling: This procedure involves reshaping the skull to allow for normal brain growth.

3. Cranial Reconstruction: This procedure involves reconstructing the skull with artificial materials to allow for normal brain growth.

4. Cranial Vault Expansion: This procedure involves using a device to slowly expand the skull to allow for normal brain growth.

5. Cranial Osteotomy: This procedure involves cutting and reshaping the skull to allow for normal brain growth.

6. Shunt Placement: This procedure involves placing a shunt to drain excess fluid from the brain and allow for normal brain growth.

What are the risk factors for Non-syndromic bicoronal craniosynostosis?

1. Family history of craniosynostosis
2. Premature birth
3. Low birth weight
4. Exposure to certain medications or drugs during pregnancy
5. Exposure to radiation during pregnancy
6. Maternal diabetes
7. Maternal smoking during pregnancy
8. Maternal alcohol consumption during pregnancy
9. Maternal obesity

Is there a cure/medications for Non-syndromic bicoronal craniosynostosis?

Non-syndromic bicoronal craniosynostosis is a type of craniosynostosis, which is a condition in which the bones of the skull fuse together too early. Treatment for this condition typically involves surgery to reshape the skull and allow for normal brain and skull growth. Medications are not typically used to treat this condition.